Jason Orange has quit Take That nine years after reforming with Mark Owen, Gary Barlow and Howard Donald.
The year-old singer announced his departure from the group this evening, leaving the remaining members as a trio.
Robbie Williams, who was the first to leave the band back in 1995 at the height of their success, will not rejoin.
In a statement, Jason explained: "I want to start by saying how proud I am of what we have achieved together over the years.
"However, at a band meeting last week I confirmed to Mark, Gary and Howard that I do not wish to commit to recording and promoting a new album. I have spent some of the best years of my life with Take That and I'd like to thank everyone who has been a part of my journey, including my band mates, who I feel are like brothers to me.
"Most especially my gratitude goes to all of the good and kind, beautiful and ever-loyal fans of the band, without whom none of this could have been possible. Thank you."
Jason also mentioned how he had started questioning his place within the band towards the end of the Progress tour in 2011, adding that "with my full knowledge and blessing" the remaining three members had started writing new songs without him at the start of this year.
"There have been no fallings out, only a decision on my part that I no longer wish to do this. I know how much Mark, Gary and Howard enjoy writing and making music, and they know that they have my full support and encouragement to continue on with what is to be another chapter for the band," he finished.
A statement from the rest of the band said:
"This is a sad day for us. Jason leaving is a huge loss both professionally and even more so personally. We first became aware of Jason’s reservations a couple of years ago but had hoped that by giving him the desired time and space he may begin to feel differently. This has not been the case and we now have to accept and fully respect his decision which we know hasn’t been an easy one. Jason’s energy and belief in what this band could achieve has made it what it is today, and we’ll forever be grateful for his enthusiasm, dedication and inspiration over the years.