Khloe Kardashian goes on HUGE Twitter rant after ‘mixing antibiotics with painkillers’ for serious infection

Khloe Kardashian FINALLY hit back at her haters in a late-night Twitter sesh that culminated in her telling one to "f**k off" and another that his dick "looks like an overinflated football".

Originally, the reality star had taken to Twitter to let her fans know she wouldn't be able to make a book signing due to illness, with doctors telling her to take it slow while they worked out what was wrong with her.

But things quickly turned sour when two followers started talking about Khloe's wedding vows and saying she should be sticking with Lamar Odom rather than dating James Harden.

Looks like the only reason she did that was so she could help make decisions about his medical care as his legal spouse.

But Khloe wasn't done telling the trolls what's up – another one who called her a "stupid whore" got the reply: "Leave me alone. You are so passive aggressive to come on my page and say that LOL pathetic cry."

After a few more righting wrongs, Khloe – or probably someone from her team, let's be honest – decided it was time for her to go to bed.

It's thought Khlo's on the medication for a 'serious staph infection' she contracted while visiting Lamar in hospital.

Get well soon, Khloe - and maybe delete the Twitter app off your phone for a bit.

Khloe Kardashian looks AMAZING stripped down for Complex sports shoot